• August 3, 2025

Research recommendations

As we develop guidance, we identify gaps and uncertainties in the evidence base which could benefit from further research. The most important unanswered questions are developed into research recommendations. Read our process and methods guide (PDF).

Browse the list below to find a topic of interest. Only research recommendations made from 2011 onwards are shown. Please contact us if you need more information.


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Showing 1 to 10 of 2,192

 Recommendation ID Recommendation Name
CG103/01Delirium assessment tools:
What is the diagnostic accuracy, and ease of implementation, of different delirium assessment tools:for people with pre-existing cognitive impairment, for example dementia, learning disability or severe depressionfor people who do not speak English as a first languagein different settings, for example emergency departments, residential care homes or virtual consultationswhen delivered by different types of health and social care practitioners, for example healthcare assistants or allied health professionals such as paramedics?
CG103/02Pharmacological prevention: In people in hospital who are at high risk of delirium, which medication (atypical antipsychotics, typical antipsychotics, benzodiazepines or acetylcholinesterase inhibitors), compared with placebo or each other, is more clinically and cost effective in preventing the development of delirium?
CG103/03Pharmacological treatment: In people in hospital who have delirium, which is the most effective medication (atypical antipsychotics, typical antipsychotics or benzodiazepines) compared with placebo or each other for treating delirium?
CG103/04Multicomponent intervention: For people in long-term care, is a multicomponent non-pharmacological intervention more clinically and cost effective than usual care in preventing the development of delirium?
CG103/05Delirium in long-term care: How common is delirium and what are its adverse outcomes in people in long-term care?
CG103/06Education programme: Does a staff education programme (compared with an educational leaflet or usual care) reduce the incidence of delirium and improve the recognition and recording of delirium in people in hospital?
CG113/1What is the relative effectiveness of sertraline compared with cognitive behavioural therapy (CBT) in people with generalised anxiety disorder (GAD) that has not responded to guided self-help and psychoeducation in a stepped-care model?
CG113/2In well-defined generalised anxiety disorder (GAD), what is the clinical and cost effectiveness of two cognitive behavioural therapy (CBT) based low-intensity interventions (CCBT and guided bibliotherapy) compared with a waiting-list control?
CG113/3For people with generalised anxiety disorder (GAD) who are ready to start a low-intensity intervention, what is the clinical effectiveness of physical activity compared with waiting-list control?
CG113/4Is chamomile/ginkgo biloba more effective than placebo in increasing response and remission rates and decreasing anxiety ratings for people with generalised anxiety disorder (GAD)?
JC

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